Do not get an Mpox shot

…unless you want a cowpox infection.

There are three Mpox shots available. Two of them (ACAM2000 and LC16) are “live virus vaccines”, meaning the viruses in the shots have supposedly been weakened so they will not provoke the disease symptoms the shot is trying to prevent. The weakening can be done by allowing animal cells to replicate the virus at different temperatures in a laboratory so that the virus will be less likely to replicate at human body temperature. They can also perform genetic modification to the virus to get “loss of function” instead of “gain of function” to make it less likely to replicate, but it still replicates enough to create an immune response. Another way is to allow the virus to replicate in laboratory cell cultures for several generations, mutating the virus into a strain that supposedly is less virulent in humans. It is important to know that living cells mutate viruses through enzymatic actions. Viruses are incapable of directing their own mutations as they are not alive and have no intelligence.

The major problem with “live virus vaccines” is that the potencies of the shots cannot be reliably controlled once they get distributed. Unless you do laser counting of the number of particles in the shot, mass spectrometry, analytical chromatography, and genetic sequencing…you have absolutely no idea what is in that syringe before they shove it into you. Potency is affected by temperature, light exposure, storage time, and humidity. Some live viral vaccines are provided in a lyophilized (freeze-dried) form and need to be reconstituted with a diluent before use. If not done properly, this can affect the potency. Some doses can revert to virulence, meaning that they are definitely potent enough to provoke the disease symptoms they are trying to prevent. Reverting to virulence has happened in the past where aggressive vaccination campaigns using live vaccines against smallpox, yellow fever, and polio resulted in outbreaks of the diseases they were trying to prevent. Ask Bill Gates, Mr. “I will eradicate polio” about that.

The two “live” Mpox vaccines do not contain the Mpox virus. They contain the vaccinia virus associated with the disease called cowpox. The idea is that the vaccinia virus is “close enough” genetically to the Mpox virus that the antibodies created against the vaccinia virus will “cross react” to the Mpox virus. There is no guarantee this cross reactivity will happen. But there is scientific evidence that allowing yourself to be injected with ACAM2000 or LC16 can result in cowpox (smallpox-like) symptoms. How do I know that? I read the vaccine package inserts, and you can too, here and here.

The third Mpox vaccine is called JYNNEOS, made by Bavarian Nordic. It is supposed to be safer because although it is still “live”, the vaccinia viruses in it have been modified so that they should not replicate in the body. The modifications can be done chemically with formaldehyde or Beta-propiolactone (BPL), or exposing the viruses to heat, ultraviolet radiation, or gamma radiation. All these methods aim to damage or alter the viral genome so that the virus particles remain intact but should not replicate inside the body.

Although JYNNEOS is supposed to be safer, looking at the vaccine package insert here, you will see that serious adverse reactions in the vaccinated group were 28% higher in the vaccinated group vs. the placebo group. You will also see that cardiac adverse effects of special interest were 550% higher in the vaccinated group.

It is estimated that half of the people who are infected by the real Mpox virus will be asymptomatic and won’t even know it happened. Most of the cases that do become symptomatic will resolve themselves with supportive care and no emergency interventions. The cases that become problematic are the ones with immunosuppression or comorbidities, and those are the people that are contraindicated from getting one of these shots anyway.

Knowing what you now know, why would you allow yourself to be injected with something that can cause myocarditis, pericarditis, tachycardia, Crohn’s disease, sarcoidosis, extraocular muscle paresis, and even some deaths as reported in VAERS, when the actual disease is manageable?

Thanks for reading, and thanks for staying smart.